Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95992 | 0.90 | — | — | |
| SCHEMBL7529643 | 0.90 | — | — | |
| Hydrogen Sulfide SCHEMBL28328604 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPK1FFAR1MAOAMAOB | |
| Fluoride SCHEMBL945714 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPK1FFAR1MAOAMAOB | |
| Ethylene SCHEMBL28310274 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPK1FFAR1MAOAMAOB | |
| Hydroquinone SCHEMBL27639375 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPK1FFAR1MAOAMAOB | |
| Dimethylamine SCHEMBL5176483 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPK1FFAR1MAOAMAOB | |
| Formic Acid SCHEMBL27454596 | 0.82 | FFAR1 (0.48) | ALDH1A1MAPK1FFAR1MAOAMAOB | |
| Methylphenylsulfide SCHEMBL29061319 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1FFAR1MAOAMAOB | |
| SCHEMBL10873673 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1FFAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | Warner-Lambert Company LLC (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003045912-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2003-06-05 | — | — | WO | disclosed |