Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597489 | 0.89 | SLC6A2 (0.41) | SLC6A2SLC6A4KCNA3SLC6A3 | |
| SCHEMBL9330906 | 0.80 | AKR1C1 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6599116 | 0.75 | SLC6A3 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9330568 | 0.74 | AKR1C1 (0.47) | — | |
| SCHEMBL6595913 | 0.74 | CHRM1 (0.38) | SLC6A2SLC6A4SLC6A3CHRM1 | |
| SCHEMBL8110728 | 0.73 | AKR1C1 (0.58) | SLC6A2SLC6A4KCNA3HCAR3HCAR2 | |
| SCHEMBL2039088 | 0.71 | KDM4E (0.38) | — | |
| SCHEMBL8183498 | 0.71 | KCNA3 (0.33) | KCNA3CHRM1 | |
| SCHEMBL2874416 | 0.71 | AKR1C1 (0.56) | KCNA3HCAR3HCAR2 | |
| SCHEMBL4944760 | 0.71 | CYP2D6 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915867-B1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOD CONSEILS RECH APPLIC (FR) | 2004-10-06 | — | — | EP | claimed |
| US-6107495-A | REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 2000-08-22 | — | — | US | disclosed |