Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597123 | 0.87 | SLC6A2 (0.41) | SLC6A3TSHRLMNASLC6A2SLC6A4 | |
| SCHEMBL6596176 | 0.82 | TP53 (0.57) | LMNAHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL6594843 | 0.82 | TP53 (0.57) | LMNAHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8189527 | 0.82 | LMNA (0.41) | TSHRLMNASLC6A2SLC6A4CHRM3 | |
| SCHEMBL9330906 | 0.79 | AKR1C1 (0.50) | SLC6A3LMNASLC6A2SLC6A4CHRM3 | |
| SCHEMBL6916553 | 0.76 | CHRM3 (0.48) | SLC6A3TSHRLMNASLC6A2SLC6A4 | |
| SCHEMBL6594703 | 0.75 | SLC6A2 (0.40) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6598744 | 0.75 | KCNA3 (0.38) | SLC6A3TSHRLMNASLC6A2CHRM3 | |
| SCHEMBL9330568 | 0.73 | AKR1C1 (0.47) | LMNACYP2D6HTTALOX15 | |
| SCHEMBL2039088 | 0.73 | KDM4E (0.38) | TSHRHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915867-B1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOD CONSEILS RECH APPLIC (FR) | 2004-10-06 | — | — | EP | claimed |
| US-6107495-A | REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 2000-08-22 | — | — | US | disclosed |