⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL4991233 | 0.86 | MAPK1 (0.40) | — | |
| SCHEMBL10940023 | 0.85 | — | — | |
| SCHEMBL7240952 | 0.85 | — | — | |
| SCHEMBL1331944 | 0.85 | — | — | |
| SCHEMBL1296 | 0.85 | — | — | |
| Ethylene Glycol SCHEMBL9733138 | 0.83 | TSHR (0.32) | — | |
| Ethylene Glycol SCHEMBL3420637 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL6829599 | 0.80 | ALDH1A1 (0.47) | — | |
| Potassium SCHEMBL8831145 | 0.80 | — | — | |
| Water SCHEMBL2929026 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038975-A2 | PROCESS FOR THE PREPARATION OF (3ARS,12BRS)-5-CHLORO-2-METHYL-2,3,3A12B-TETRAHYDRO-1HDIBENZO[2,3:6,7] OXEPINO [4,5-C]PYRROLE MALEATE AND IT'S PHARMACEUTICAL COMPOSITION THEREOF | MSN LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| US-20240199582-A1 | INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE | RHIZEN PHARMACEUTICALS AG (CH) | 2024-06-20 | — | — | US | disclosed |
| CN-114829367-B | Functionalization of 1, 3-alpha-diene (I) | 帝斯曼知识产权资产管理有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11952341-B2 | Method of preparing high chiral purity lactam intermediate and brivaracetam | YANGZHOU AORUITE PHARMACEUTICAL CO., LTD. (CN) | 2024-04-09 | — | — | US | disclosed |
| EP-4324819-A2 | NEW INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | DSM IP Assets B.V. (NL) | 2024-02-21 | — | — | EP | disclosed |
| US-11851404-B2 | Intermediates for the vitamin A synthesis | DSM IP ASSETS B.V. (NL) | 2023-12-26 | — | — | US | disclosed |
| CN-116854588-A | Preparation method of propylene glycol methyl ether acetate | 上海邦高化学有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20230090098-A1 | FUNCTIONALISATION OF 1,3-ALPHA-DIENES (I) | DSM IP ASSETS B.V. (NL) | 2023-03-23 | — | — | US | disclosed |
| US-20230066606-A1 | METHOD OF PREPARING HIGH CHIRAL PURITY LACTAM INTERMEDIATE AND BRIVARACETAM | YANGZHOU LIANAO BIOMEDICAL CO., LTD. (CN) | 2023-03-02 | — | — | US | disclosed |
| US-20220169590-A1 | INTERMEDIATES FOR THE VITAMIN A SYNTHESIS | DSM IP ASSETS BV (NL) | 2022-06-02 | — | — | US | disclosed |
| US-4808210-A | WEED CONTROL | ROUSSEL UCLAF (FR) | 1989-02-28 | — | — | US | disclosed |
| US-4788306-A | Fluorooxirane carboxylates as hypoglycemic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4788304-A | ANTIALLERGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4731358-A | β-carbolines and their use as tranquilizers | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |
| US-4695580-A | Phenylserine derivatives and processes for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| US-4665202-A | Flavene and thioflavene derivatives | ZYMA SA (CH) | 1987-05-12 | — | — | US | disclosed |
| EP-0185814-A2 | Phenylserine derivatives and processes for their preparation | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0140830-A2 | Pharmaceutical preparations containing flavene or thioflavene derivatives, the use thereof, novel flavenes and thioflavenes, and processes for their manufacture | Zyma SA (CH) | 1985-05-08 | — | — | EP | disclosed |
| US-4289781-A | Anti-psychotic phthalimidine derivatives | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1981-09-15 | — | — | US | disclosed |
| EP-0026749-A1 | Phthalimidine derivatives and pharmaceutical compositions containing them | Astra Läkemedel Aktiebolag (SE) | 1981-04-08 | — | — | EP | disclosed |