Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RRM1 | P23921 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595011 | 1.00 | ALDH1A1 (0.51) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 | |
| SCHEMBL7915285 | 0.78 | ERN1 (0.70) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 | |
| SCHEMBL7915280 | 0.78 | ERN1 (0.70) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 | |
| SCHEMBL6595070 | 0.77 | RIOK2 (0.57) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 | |
| SCHEMBL6595072 | 0.77 | RIOK2 (0.57) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 | |
| SCHEMBL6593326 | 0.74 | MAPT (0.48) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6593322 | 0.74 | MAPT (0.48) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL28503936 | 0.71 | RRM1 (0.63) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 | |
| SCHEMBL6591213 | 0.69 | CDC7 (0.46) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 | |
| SCHEMBL6591217 | 0.69 | CDC7 (0.46) | ALDH1A1ALOX15TP53CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |