Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600395 | 0.88 | NPC1 (0.34) | NPC1DPP4RAB9ANR1H4DPP7 | |
| SCHEMBL6594174 | 0.86 | NPC1 (0.40) | NPC1GPR6MAPTDPP4MEN1 | |
| SCHEMBL8492339 | 0.84 | NPC1 (0.39) | NPC1GPR6MAPTDPP4MEN1 | |
| SCHEMBL8762846 | 0.84 | LMNA (0.42) | NPC1GPR6MAPTDPP4MEN1 | |
| SCHEMBL8492902 | 0.83 | NPC1 (0.38) | NPC1GPR6MAPTDPP4MEN1 | |
| SCHEMBL6596749 | 0.83 | GPBAR1 (0.36) | NPC1ALDH1A1PPARGNPSR1RXFP1 | |
| SCHEMBL8492665 | 0.82 | NPC1 (0.38) | NPC1GPR6MAPTDPP4MEN1 | |
| SCHEMBL8494679 | 0.82 | NR1H4 (0.40) | NPC1GPR6MAPTMEN1KMT2A | |
| SCHEMBL6594562 | 0.80 | GPBAR1 (0.32) | GPBAR1 | |
| SCHEMBL8492287 | 0.79 | DPP4 (0.36) | NPC1GPR6MAPTDPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901479-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-11 | — | — | EP | claimed |
| US-6297198-B1 | COMPOUNDS WITH SULFUR GROUPS ON ISOXAZOLE RINGS AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-10-02 | — | — | US | claimed |
| EP-0901479-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1999-03-17 | — | — | EP | claimed |
| WO-1997043270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1997-11-20 | — | — | WO | claimed |
| EP-0901479-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-11 | — | — | EP | disclosed |
| US-6297198-B1 | COMPOUNDS WITH SULFUR GROUPS ON ISOXAZOLE RINGS AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-10-02 | — | — | US | disclosed |
| EP-0901479-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1997-11-20 | — | — | WO | disclosed |