Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | CCR4 | P51679 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SORD | Q00796 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418612 | 0.79 | SORD (0.49) | SORDHRH1MEN1ALDH1A1MAPK1 | |
| SCHEMBL9336873 | 0.75 | HRH1 (0.50) | SORDHRH1MEN1ALDH1A1MAPK1 | |
| SCHEMBL2242665 | 0.73 | SMN1; SMN2 (0.52) | SORDHRH1MEN1ALDH1A1MAPK1 | |
| SCHEMBL778332 | 0.73 | SMN1; SMN2 (0.52) | SORDHRH1MEN1ALDH1A1MAPK1 | |
| SCHEMBL9073359 | 0.71 | HRH1 (0.56) | HRH1MEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL12903094 | 0.70 | KMT2A (0.55) | HRH3HRH4KMT2A | |
| SCHEMBL19034085 | 0.69 | — | — | |
| SCHEMBL13942560 | 0.69 | PHGDH (0.52) | HRH3MEN1ALDH1A1KMT2A | |
| SCHEMBL25401723 | 0.69 | PDE10A (0.38) | SORDALDH1A1KMT2A | |
| SCHEMBL21954045 | 0.69 | HRH1 (0.50) | HRH3HRH1CYP11B2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |