Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242665 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL9336873 | 0.97 | HRH1 (0.50) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL1090112 | 0.95 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL8422457 | 0.95 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL28998684 | 0.95 | SMN1; SMN2 (0.58) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL9073359 | 0.92 | HRH1 (0.56) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL9418612 | 0.87 | SORD (0.49) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL1066847 | 0.85 | ALDH1A1 (0.49) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL19295119 | 0.85 | MAPK1 (0.47) | SMN1; SMN2TDP1USP2MEN1KMT2A | |
| SCHEMBL778177 | 0.83 | USP2 (0.81) | SMN1; SMN2TDP1USP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584757-B2 | MK2 inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2023-02-21 | — | — | US | disclosed |
| US-11584757-B2 | MK2 inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2023-02-21 | — | — | US | disclosed |
| EP-3912981-A1 | MK2 INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-11-24 | — | — | EP | disclosed |
| EP-3912981-A1 | MK2 INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-11-24 | — | — | EP | disclosed |
| EP-3193611-B1 | MK2 INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-03-24 | — | — | EP | disclosed |
| EP-3193611-B1 | MK2 INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-03-24 | — | — | EP | disclosed |
| US-20210053984-A1 | MK2 INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2021-02-25 | — | — | US | disclosed |
| US-20210053984-A1 | MK2 INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2021-02-25 | — | — | US | disclosed |
| CN-106998692-B | MK2 inhibitors and uses thereof | 西建卡尔有限责任公司 | 2020-09-08 | — | — | CN | disclosed |
| US-10577380-B2 | MK2 inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2020-03-03 | — | — | US | disclosed |
| EP-0326082-B1 | FLAME-RETARDANT POLYPROPYLENE RESIN COMPOSITION | Chisso Corporation (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5158999-A | Oligomers and-or polymers containing triazines and phosphine oxide units in the backbone | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0413613-A1 | Flame retardants | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4966931-A | POLYAMMONIUM PHOSPHATES, POLYTRIAZINES, POLYETHYLENE BLENDS | CHISSO CORPORATION (JP) | 1990-10-30 | — | — | US | disclosed |
| US-4939243-A | Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| EP-0326082-A2 | Flame-retardant polypropylene resin composition | Chisso Corporation (JP) | 1989-08-02 | — | — | EP | disclosed |
| US-4675353-A | PHOTOSTABILIZERS | THE BFGOODRICH COMPANY (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0189877-A2 | Hindered 2-keto-1,4-diazacycloalkane oligomers containing triazine rings or ester groups and compositions stabilized thereby | The B.F. GOODRICH Company (US) | 1986-08-06 | — | — | EP | disclosed |
| EP-0084849-B1 | WATER SOLUBLE COPPER COMPLEXES OF DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0084849-A2 | Water soluble copper complexes of disazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577380-B2 | MK2 inhibitors and uses thereof | MKNK2, DUSP2, MKNK1 | SMN1; SMN2 4098/4885TDP1 3334/4885USP2 874/4885 |
| US-11584757-B2 | MK2 inhibitors and uses thereof | MKNK2, DUSP2, MKNK1 | SMN1; SMN2 4098/4885TDP1 3334/4885USP2 874/4885 |
| US-20210053984-A1 | MK2 INHIBITORS AND USES THEREOF | MKNK2, DUSP2, MKNK1 | SMN1; SMN2 4098/4885TDP1 3334/4885USP2 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.