Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595140 | 1.00 | CTSV (0.42) | CTSVCTSLPOLBMCL1SENP8 | |
| SCHEMBL6593975 | 0.93 | CYP11B1 (0.46) | CTSVCTSLPOLBPIN1CYP19A1 | |
| SCHEMBL6080661 | 0.91 | APP (0.43) | CTSVCTSLPOLBAPPCYP19A1 | |
| SCHEMBL6593611 | 0.90 | XDH (0.43) | CTSVCTSLPOLBMCL1SENP8 | |
| SCHEMBL6593616 | 0.90 | XDH (0.43) | CTSVCTSLPOLBMCL1SENP8 | |
| SCHEMBL6614590 | 0.90 | CTSV (0.39) | CTSVCTSLPOLBMCL1SENP8 | |
| SCHEMBL6594775 | 0.85 | CTSV (0.44) | CTSVCTSLPOLBMCL1SENP8 | |
| SCHEMBL6594175 | 0.85 | CTSV (0.44) | CTSVCTSLPOLBMCL1SENP8 | |
| SCHEMBL6594769 | 0.85 | CTSV (0.44) | CTSVCTSLPOLBMCL1SENP8 | |
| SCHEMBL6594169 | 0.85 | CTSV (0.44) | CTSVCTSLPOLBMCL1SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |