Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.35 |
| ▸ | IGFBP5 | P24593 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | IGFBP1 | P08833 | 1/20 | 0.35 |
| ▸ | IGFBP2 | P18065 | 1/20 | 0.35 |
| ▸ | IGFBP4 | P22692 | 1/20 | 0.35 |
| ▸ | IGFBP6 | P24592 | 1/20 | 0.35 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976004 | 0.85 | KDM4E (0.53) | KDM4EMAPTRAB9ATDP1KMT2A | |
| SCHEMBL6080271 | 0.84 | KDM4E (0.37) | KDM4EMAPTRAB9ATDP1KMT2A | |
| SCHEMBL6080750 | 0.81 | KDM4E (0.46) | KDM4EMAPTRAB9ATDP1KMT2A | |
| SCHEMBL18682034 | 0.79 | KDM4E (0.58) | KDM4EMAPTRAB9ATDP1KMT2A | |
| SCHEMBL6080950 | 0.77 | KDM4E (0.46) | KDM4EMAPTRAB9ATDP1KMT2A | |
| SCHEMBL6080760 | 0.76 | KDM4E (0.56) | KDM4EMAPTRAB9ATDP1KMT2A | |
| SCHEMBL6079629 | 0.76 | THRA (0.45) | KDM4EKMT2AMCL1ALDH1A1 | |
| SCHEMBL6080475 | 0.75 | KDM4E (0.44) | KDM4EMAPTRAB9ATDP1KMT2A | |
| Xanthurenate SCHEMBL29394132 | 0.75 | KDM4E (0.59) | KDM4EMAPTRAB9ATDP1KMT2A | |
| Xanthurenate SCHEMBL29911018 | 0.75 | KDM4E (0.59) | KDM4EMAPTRAB9ATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |