Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728477 | 1.00 | MAOA (0.34) | MAOAMAOBPKM | |
| SCHEMBL6597582 | 0.88 | MAOA (0.34) | MAOAMAOB | |
| SCHEMBL31358088 | 0.84 | MAOA (0.36) | MAOAMAOBPKM | |
| SCHEMBL1356030 | 0.82 | MAOA (0.34) | MAOAMAOB | |
| SCHEMBL31550334 | 0.81 | PPARD (0.33) | MAOAMAOB | |
| SCHEMBL4798260 | 0.81 | HTR2A (0.36) | — | |
| SCHEMBL16094835 | 0.79 | POLB (0.32) | — | |
| SCHEMBL7479177 | 0.78 | MAOA (0.57) | MAOAMAOB | |
| SCHEMBL31413592 | 0.76 | MAOA (0.41) | MAOAMAOB | |
| SCHEMBL6595280 | 0.75 | LMNA (0.31) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1204660-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009126-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |