Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035134 | 0.84 | AOC1 (0.59) | AOC1AOC3ALDH1A1KDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL8375149 | 0.72 | L3MBTL1 (0.42) | ALDH1A1KDM4EMAPTMEN1KDM6B | |
| SCHEMBL23540496 | 0.72 | AOC1 (0.47) | AOC1AOC3ALDH1A1KDM4EMAPT | |
| SCHEMBL30015187 | 0.72 | AOC1 (0.47) | AOC1AOC3ALDH1A1KDM4EMAPT | |
| SCHEMBL2999880 | 0.70 | AOC1 (0.53) | AOC1AOC3ALDH1A1KDM4EMAPT | |
| SCHEMBL30210557 | 0.70 | — | — | |
| SCHEMBL5748797 | 0.70 | — | — | |
| SCHEMBL3326582 | 0.70 | AOC1 (0.57) | AOC1AOC3ALDH1A1KDM4EMAPT | |
| Trifluoroacetic Acid SCHEMBL8375150 | 0.69 | KDM4E (0.39) | ALDH1A1KDM4EMAPTMEN1KDM6B | |
| SCHEMBL23674697 | 0.69 | KDM4C (0.49) | ALDH1A1KDM4EMAPTMEN1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414801-A1 | ARYLAMINES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH GSK-3 | AstraZeneca AB (SE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003004472-A1 | ARYLAMINES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH GSK-3 | ASTRAZENECA AB (SE) | 2003-01-16 | — | — | WO | disclosed |