⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900091 | 1.00 | — | — | |
| SCHEMBL10970 | 0.70 | — | — | |
| SCHEMBL88594 | 0.70 | — | — | |
| SCHEMBL29788434 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL10877970 | 0.69 | CYP2A6 (0.40) | — | |
| Potassium SCHEMBL17350115 | 0.69 | CYP2A6 (0.40) | — | |
| SCHEMBL17350114 | 0.69 | CYP2A6 (0.40) | — | |
| Hydrochloric Acid SCHEMBL3872997 | 0.69 | CYP2A6 (0.40) | — | |
| SCHEMBL11068559 | 0.69 | CYP2A6 (0.40) | — | |
| Lithium SCHEMBL11068561 | 0.69 | CYP2A6 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240009190-A1 | COMBINATION CANCER THERAPY USING CHK INHIBITOR | Shanghai Huayu Biotechnology Co., Ltd. (CN) | 2024-01-11 | — | — | US | claimed |
| US-20230049029-A1 | COMBINATION CANCER THERAPY USING CHK INHIBITOR | Shanghai Huayu Biotechnology Co., Ltd. (CN) | 2023-02-16 | — | — | US | claimed |
| EP-4087561-A2 | COMBINATION CANCER THERAPY USING CHK INHIBITOR | Shanghai Huayu Biotechnology Co., Ltd. (CN) | 2022-11-16 | — | — | EP | claimed |
| EP-4087563-A1 | COMBINATION CANCER THERAPY USING CHK INHIBITOR | Shanghai Huayu Biotechnology Co., Ltd. (CN) | 2022-11-16 | — | — | EP | claimed |
| CN-119775321-A | 4, 7-Diaryl thieno [2,3-d ] pyridazine iridium complex, and preparation method and application thereof | 湖北文理学院 | 2025-04-08 | — | — | CN | disclosed |
| US-12012467-B2 | Small molecule DCN1 inhibitors and therapeutic methods using the same | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-18 | — | — | US | disclosed |
| EP-3801499-B1 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS INC (US) | 2024-02-28 | — | — | EP | disclosed |
| US-20240009190-A1 | COMBINATION CANCER THERAPY USING CHK INHIBITOR | Shanghai Huayu Biotechnology Co., Ltd. (CN) | 2024-01-11 | — | — | US | disclosed |
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3498701-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2023-02-22 | — | — | EP | disclosed |
| US-20230049029-A1 | COMBINATION CANCER THERAPY USING CHK INHIBITOR | Shanghai Huayu Biotechnology Co., Ltd. (CN) | 2023-02-16 | — | — | US | disclosed |
| EP-4087561-A2 | COMBINATION CANCER THERAPY USING CHK INHIBITOR | Shanghai Huayu Biotechnology Co., Ltd. (CN) | 2022-11-16 | — | — | EP | disclosed |
| US-7166408-B2 | Image forming method using photothermographic material | FUJIFILM CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |
| US-7166408-B2 | Image forming method using photothermographic material | FUJIFILM CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20070003885-A1 | Black and white photothermographic material and image forming method | FUJI PHOTO FILM CO., LTD. | 2007-01-04 | — | — | US | disclosed |
| US-20070003885-A1 | Black and white photothermographic material and image forming method | FUJI PHOTO FILM CO., LTD. | 2007-01-04 | — | — | US | disclosed |
| CN-1769282-A | Substituted pyridines and pyridazines with angiogenesis inhibiting activity | BAYER PHARMACEUTICALS CORP (US) | 2006-05-10 | — | — | CN | disclosed |
| CN-1769283-A | Substituted pyridines and pyridazines with angiogenesis inhibiting activity | BAYER PHARMACEUTICALS CORP (US) | 2006-05-10 | — | — | CN | disclosed |
| CN-1420879-A | Substituted pyridines and pyridazines having angiogenesis inhibiting activity | BAYER AG (US) | 2003-05-28 | — | — | CN | disclosed |
| CN-88103535-A | Tricyclic pyridine ketone derivatives and preparation method thereof | — | 1988-12-28 | — | — | CN | disclosed |