⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712298 | 1.00 | LMNA (0.55) | — | |
| SCHEMBL1995351 | 0.92 | — | — | |
| SCHEMBL95733 | 0.85 | TSHR (0.61) | — | |
| SCHEMBL107940 | 0.85 | TSHR (0.61) | — | |
| SCHEMBL4397606 | 0.85 | TSHR (0.61) | — | |
| SCHEMBL4399689 | 0.85 | TSHR (0.61) | — | |
| SCHEMBL277225 | 0.85 | TSHR (0.61) | — | |
| SCHEMBL7699808 | 0.85 | TSHR (0.61) | — | |
| SCHEMBL7697182 | 0.85 | TSHR (0.61) | — | |
| SCHEMBL9206028 | 0.85 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| EP-1069124-B1 | 2-Benzimidazolylamine compounds as ORL1-receptor agonists | PFIZER (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |
| US-6340681-B1 | USEFUL AS ANALGESICS IN MAMMALS | PFIZER INC | 2002-01-22 | — | — | US | disclosed |