Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.46 |
| ▸ | RARG | P13631 | 11/20 | 0.46 |
| ▸ | RARA | P10276 | 10/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588111 | 0.91 | RARA (0.48) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL1140748 | 0.90 | RARA (0.48) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL6590257 | 0.89 | RARA (0.43) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL6592559 | 0.87 | RARA (0.46) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL6594145 | 0.86 | RARB (0.60) | RARBRARGRARACYP3A4 | |
| SCHEMBL6588514 | 0.84 | RARA (0.45) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL6590554 | 0.84 | RARA (0.39) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL6590745 | 0.81 | RARA (0.40) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL6592790 | 0.81 | RARB (0.46) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL6591846 | 0.81 | RARA (0.48) | RARBRARGRARACYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042313-B1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST LIKE ACTIVITY | ALLERGAN INC (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-1042313-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST LIKE ACTIVITY | Allergan Sales, Inc. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033821-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES HAVING RETINOID ANTAGONIST-LIKE ACTIVITY | ALLERGAN SALES, INC. (US) | 1999-07-08 | — | — | WO | disclosed |