Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596248 | 1.00 | MMP2 (0.37) | MMP2MMP12GPR35CTSBEIF4A1 | |
| SCHEMBL6080639 | 0.91 | APP (0.43) | MMP2MMP12CTSBEIF4A1ALDH1A1 | |
| SCHEMBL6591840 | 0.83 | MRGPRX4 (0.43) | MMP2MMP12ALDH1A1SMN1; SMN2 | |
| SCHEMBL6597779 | 0.81 | CTSV (0.41) | POLBSENP8SENP7SENP6TDP1 | |
| SCHEMBL28423586 | 0.80 | MEN1 (0.40) | GPR35EIF4A1ALDH1A1SMN1; SMN2AURKA | |
| SCHEMBL6616134 | 0.80 | MMP2 (0.36) | MMP2MMP12GPR35CTSBEIF4A1 | |
| SCHEMBL6614590 | 0.79 | CTSV (0.39) | MMP2MMP12POLBSENP8SENP7 | |
| SCHEMBL6080643 | 0.79 | KMT2A (0.38) | MMP2MMP12GPR35EIF4A1ALDH1A1 | |
| SCHEMBL6592928 | 0.78 | CTSV (0.47) | POLBSENP8SENP7SENP6TDP1 | |
| SCHEMBL6592924 | 0.78 | CTSV (0.47) | POLBSENP8SENP7SENP6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |