SCHEMBL6596280

SCHEMBL6596280

C=CC(O)(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.38
TGM2 P21980 3/20 0.36
F13A1 P00488 1/20 0.36
LMNA P02545 1/20 0.36
TGM1 P22735 1/20 0.36
TGM3 Q08188 1/20 0.36
ALOX15 P16050 2/20 0.36
CYP19A1 P11511 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CYP2C19 P33261 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
TSHR P16473 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
MMP9 P14780 1/20 0.32
OGG1 O15527 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7681435 0.92 ALOX15 (0.52) TGM2F13A1LMNATGM1TGM3
SCHEMBL11619282 0.92 KDM4E (0.41) TGM2F13A1LMNATGM1TGM3
SCHEMBL11293244 0.81 CYP19A1 (0.44) CYP19A1CYP2C19SMN1; SMN2ALDH1A1MAPK1
SCHEMBL11372789 0.80 CYP19A1 (0.43) LMNACYP19A1SMN1; SMN2ALDH1A1MAPK1
SCHEMBL29963919 0.76 RAB9A (0.43) TGM2LMNACYP19A1CYP2C19CES2
SCHEMBL4632476 0.76 MEN1 (0.50) CYP2A6LMNACYP19A1TSHRMAPK1
SCHEMBL1246315 0.76 TRPV1 (0.32) CA1CA2
SCHEMBL30193363 0.76 TSHR (0.44) TGM2LMNACYP19A1CA1CA2
SCHEMBL11850659 0.76 KDM4E (0.42) CYP2A6TGM2ALOX15CYP19A1CA1
SCHEMBL11850657 0.76 KDM4E (0.42) CYP2A6TGM2ALOX15CYP19A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805148-B Synthesis method of beta-carbonyl sulfide compound 陇东学院 2024-04-23 CN disclosed
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN disclosed
CN-114805148-A Synthesis method of beta-carbonyl thioether compound 陇东学院 2022-07-29 CN disclosed
EP-1414778-A1 NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. NOVO NORDISK A/S (DK) 2004-05-06 EP disclosed
WO-2003011807-A1 NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC. NOVO NORDISK A/S (DK) 2003-02-13 WO disclosed