Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1195021 | 0.99 | HPGDS (0.52) | HPGDSALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL13426115 | 0.79 | SOD1 (0.49) | HPGDSKCNH2 | |
| SCHEMBL6597674 | 0.79 | HPGDS (0.53) | HPGDSALDH1A1CYP1A2CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL1194018 | 0.78 | HPGDS (0.52) | HPGDSALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL2317822 | 0.77 | CYP3A4 (0.54) | HPGDSALDH1A1CYP1A2CYP3A4TDP1 | |
| SCHEMBL27730924 | 0.73 | HPGDS (0.78) | HPGDSALDH1A1CYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL7379027 | 0.73 | CYP1A2 (0.50) | HPGDSALDH1A1CYP1A2CYP3A4CYP2E1 | |
| SCHEMBL18292685 | 0.73 | SMN1; SMN2 (0.54) | HPGDSALDH1A1CYP1A2CYP3A4HPGD | |
| Hydrochloric Acid SCHEMBL27514609 | 0.72 | HPGDS (0.76) | HPGDSALDH1A1CYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL3396037 | 0.72 | FFAR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |