Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TNF | P01375 | 3/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596389 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6692166 | 0.84 | KMT2A (0.39) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6596143 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6596139 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6596147 | 0.74 | MAPT (0.60) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6596145 | 0.74 | MAPT (0.60) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6594134 | 0.73 | ALDH1A1 (0.63) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6594138 | 0.73 | ALDH1A1 (0.63) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6595740 | 0.72 | KDM4E (0.81) | KDM4EALDH1A1MAPTLMNATNF | |
| SCHEMBL6595735 | 0.72 | KDM4E (0.81) | KDM4EALDH1A1MAPTLMNATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |