Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596385 | 0.84 | KDM4E (0.54) | KMT2AMEN1POLBPDE3BPDE3A | |
| SCHEMBL6596389 | 0.84 | KDM4E (0.54) | KMT2AMEN1POLBPDE3BPDE3A | |
| SCHEMBL6597415 | 0.80 | PDE3B (0.44) | KMT2AMEN1PDE3BPDE3AALDH1A1 | |
| SCHEMBL6597409 | 0.80 | PDE3B (0.44) | KMT2AMEN1PDE3BPDE3AALDH1A1 | |
| SCHEMBL6661728 | 0.72 | TNF (0.39) | KMT2AMEN1POLBPDE3BPDE3A | |
| SCHEMBL6664825 | 0.72 | TNF (0.39) | KMT2AMEN1POLBPDE3BPDE3A | |
| SCHEMBL6589681 | 0.70 | KDM4E (0.63) | KMT2APDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL6589679 | 0.70 | KDM4E (0.63) | KMT2APDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL6593981 | 0.67 | TNF (0.35) | KMT2AMEN1PDE3BPDE3AALDH1A1 | |
| SCHEMBL6593976 | 0.67 | TNF (0.35) | KMT2AMEN1PDE3BPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |