⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593653 | 0.83 | — | — | |
| SCHEMBL6595885 | 0.75 | TP53 (0.46) | — | |
| SCHEMBL6595453 | 0.74 | MAOB (0.36) | — | |
| SCHEMBL6596507 | 0.73 | — | — | |
| SCHEMBL6590728 | 0.72 | THRB (0.49) | — | |
| SCHEMBL6593518 | 0.72 | ESR1 (0.50) | — | |
| SCHEMBL6594796 | 0.71 | FFAR1 (0.35) | — | |
| SCHEMBL6592579 | 0.70 | FLT3 (0.44) | — | |
| SCHEMBL6597257 | 0.68 | KDM4E (0.50) | — | |
| SCHEMBL6594401 | 0.68 | APP (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063235-B1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LTD (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-20030186976-A1 | Benzofurylpyrone derivatives | TEIJIN LIMITED, MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2003-10-02 | — | — | US | disclosed |
| EP-1063235-A1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-12-27 | — | — | EP | disclosed |