Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535849 | 0.88 | KDM4E (0.51) | DYRK1AHDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL6567169 | 0.77 | ALDH1A1 (0.52) | DYRK1AHDAC2HDAC8HDAC6KDM4E | |
| SCHEMBL1249257 | 0.75 | SMN1; SMN2 (0.53) | HDAC2HDAC8KDM4EALDH1A1HPGD | |
| SCHEMBL29106097 | 0.74 | CHEK1 (0.52) | PRKAG1PRKAA1PRKAB1KDM4EALDH1A1 | |
| SCHEMBL5885105 | 0.71 | MCL1 (0.67) | HDAC2HDAC8HDAC4SMN1; SMN2MCL1 | |
| SCHEMBL20681140 | 0.71 | PIM1 (0.46) | KDM4EALDH1A1HPGDPOLBMAPT | |
| SCHEMBL5047379 | 0.71 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL6565865 | 0.71 | EGLN1 (0.57) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL6597008 | 0.69 | HDAC2 (0.53) | HDAC2HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL6564111 | 0.69 | MTNR1B (0.48) | KDM4EALDH1A1HPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |