Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.63 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.60 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.60 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597278 | 1.00 | P2RY12 (0.63) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL13902897 | 0.92 | P2RY12 (0.64) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL14394700 | 0.92 | P2RY12 (0.64) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL26347621 | 0.88 | BMPR1B (0.62) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL11992626 | 0.88 | BMPR1B (0.62) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL17014896 | 0.88 | BMPR1B (0.62) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL7203911 | 0.88 | P2RY12 (0.62) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL30666149 | 0.88 | P2RY12 (0.81) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL17824398 | 0.88 | P2RY12 (0.81) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL8905007 | 0.87 | PRKAB2 (0.67) | P2RY12DNPH1P2RY2P2RY1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140038181-A1 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION | TRILINK BIOTECHNOLOGIES, INC. | 2014-02-06 | — | — | US | disclosed |
| EP-0815114-B1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | UNIV DUKE (US) | 2004-05-12 | — | — | EP | disclosed |
| US-5908926-A | 5'to 3' nucleic acid synthesis using 3'-photoremovable protecting group | DUKE UNIVERSITY (US) | 1999-06-01 | — | — | US | disclosed |
| EP-0815114-A4 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | UNIV DUKE (US) | 1999-02-24 | — | — | EP | disclosed |
| EP-0815114-A1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | DUKE UNIVERSITY (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996028457-A1 | NUCLEIC ACID SYNTHESIS USING PHOTOREMOVABLE PROTECTING GROUPS | DUKE UNIVERSITY (US) | 1996-09-19 | — | — | WO | disclosed |