⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052844 | 0.79 | — | — | |
| SCHEMBL3361966 | 0.76 | — | — | |
| SCHEMBL5224314 | 0.76 | — | — | |
| SCHEMBL29127465 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL201249 | 0.74 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL7350919 | 0.74 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL201248 | 0.74 | KMT2A (0.41) | — | |
| SCHEMBL27256699 | 0.74 | — | — | |
| SCHEMBL3989278 | 0.73 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6392619 | 0.73 | KMT2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102285936-A | 4-thiazolidone carboxylic acid derivative and preparation method and application thereof | — | 2011-12-21 | — | — | CN | claimed |
| CN-102285936-A | 4-thiazolidone carboxylic acid derivative and preparation method and application thereof | — | 2011-12-21 | — | — | CN | disclosed |
| EP-1228061-A4 | DIPEPTIDYL PEPTIDASE IV INHIBITORS AND METHODS OF MAKING AND USING DIPEPTIDYL PEPTIDASE IV INHIBITORS | GUILFORD PHARM INC (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1228061-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS AND METHODS OF MAKING AND USING DIPEPTIDYL PEPTIDASE IV INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001034594-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS AND METHODS OF MAKING AND USING DIPEPTIDYL PEPTIDASE IV INHIBITORS | GUILFORD PHARMACEUTICALS, INC. (US) | 2001-05-17 | — | — | WO | disclosed |