Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 9/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 9/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 9/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 9/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.37 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598946 | 0.91 | GRIA1 (0.44) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6600127 | 0.89 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6598978 | 0.87 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6597213 | 0.76 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6596000 | 0.76 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6592034 | 0.75 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6598151 | 0.70 | FPR2 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6595172 | 0.70 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6598036 | 0.68 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6598356 | 0.66 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156044-B1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6562839-B1 | Effective for the therapy of disorder of cerebral nerve cells as antagonists against excitatory amino acid receptors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1156044-A1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |