Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | IL6ST | P40189 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13986788 | 0.97 | PPARA (0.47) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL20695126 | 0.94 | PPARA (0.47) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL20695124 | 0.94 | PPARA (0.47) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL19423252 | 0.94 | PPARA (0.47) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL19423219 | 0.94 | PPARA (0.47) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL20695123 | 0.94 | PPARA (0.47) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL13986870 | 0.88 | PPARA (0.52) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL2070699 | 0.87 | IL6ST (0.54) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL6601336 | 0.87 | IL6ST (0.54) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL15587060 | 0.86 | PPARA (0.51) | PPARAIL6STFAAHNAAAIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080082-B1 | INTERMEDIATES FOR THE SYNTHESIS OF EPOTHILONES AND METHODS FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2004-10-06 | — | — | EP | disclosed |
| US-6350878-B1 | BASIFICATION AND IODINATION OF ALDEHYDE | NOVARTIS AG (CH) | 2002-02-26 | — | — | US | disclosed |