Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | UGCG | Q16739 | 2/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601336 | 1.00 | IL6ST (0.54) | IL6STSTAT3IDH1NAAAGBA1 | |
| SCHEMBL30984038 | 0.94 | IL6ST (0.56) | IL6STSTAT3IDH1NAAAAGTR2 | |
| SCHEMBL6597608 | 0.87 | PPARA (0.47) | IL6STIDH1NAAAGBA1UGCG | |
| SCHEMBL8826143 | 0.86 | IL6ST (0.59) | IL6STSTAT3IDH1NAAAFAAH | |
| SCHEMBL30984014 | 0.85 | NAAA (0.51) | IL6STSTAT3IDH1NAAAFAAH | |
| SCHEMBL7794117 | 0.84 | IL6ST (0.49) | IL6STSTAT3IDH1NAAAGBA1 | |
| SCHEMBL6598726 | 0.84 | NAAA (0.53) | IL6STSTAT3IDH1NAAAGBA1 | |
| SCHEMBL2072708 | 0.84 | NAAA (0.53) | IL6STSTAT3IDH1NAAAGBA1 | |
| SCHEMBL13986788 | 0.84 | PPARA (0.47) | IL6STIDH1NAAAGBA1UGCG | |
| SCHEMBL12937771 | 0.82 | IL6ST (0.55) | IL6STSTAT3IDH1GBA1GBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893268-B2 | Epithiolone analogues | UNIVERSITY OF TOLEDO (US) | 2011-02-22 | — | — | US | disclosed |
| US-20090258904-A1 | Epithiolone Analogues | UNIVERSITY OF TOLEDO | 2009-10-15 | — | — | US | disclosed |
| WO-2007015929-A2 | EPOTHILONE ANALOGUES | UNIVERSITY OF TOLEDO (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258904-A1 | Epithiolone Analogues | ESRRB, ESR2, ESRRA | IL6ST 2627/4885STAT3 2254/4885IDH1 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.