SCHEMBL19423219

SCHEMBL19423219

C[C@@H](CCOCc1ccccc1)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.47
IL6ST P40189 1/20 0.41
FAAH O00519 1/20 0.41
NAAA Q02083 1/20 0.38
IDH1 O75874 7/20 0.38
AGTR2 P50052 2/20 0.37
CYP2C19 P33261 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
ALDH1A1 P00352 1/20 0.35
ABCB1 P08183 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20695123 1.00 PPARA (0.47) PPARAIL6STFAAHNAAAIDH1
SCHEMBL20695126 1.00 PPARA (0.47) PPARAIL6STFAAHNAAAIDH1
SCHEMBL19423252 1.00 PPARA (0.47) PPARAIL6STFAAHNAAAIDH1
SCHEMBL20695124 1.00 PPARA (0.47) PPARAIL6STFAAHNAAAIDH1
SCHEMBL6597608 0.94 PPARA (0.47) PPARAIL6STFAAHNAAAIDH1
SCHEMBL13986788 0.93 PPARA (0.47) PPARAIL6STFAAHNAAAIDH1
SCHEMBL20708959 0.87 PPARA (0.40) PPARAIL6STFAAHNAAAIDH1
SCHEMBL22793540 0.87 PPARA (0.41) PPARAIL6STFAAHNAAAIDH1
SCHEMBL30984038 0.86 IL6ST (0.56) IL6STFAAHNAAAIDH1AGTR2
SCHEMBL21724415 0.85 PPARA (0.52) PPARAIL6STFAAHNAAAIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440046-B Synthetic method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest phyllocladia persica 塔里木大学 2022-09-16 CN claimed
CN-111440046-A Synthesis method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest peach leaf miner 塔里木大学 2020-07-24 CN claimed
CN-111440046-B Synthetic method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest phyllocladia persica 塔里木大学 2022-09-16 CN disclosed
EP-3437640-B1 AGENT FOR TREATING SYNUCLEINOPATHY UNIV TOHOKU (JP) 2021-11-24 EP disclosed
EP-3437640-B1 AGENT FOR TREATING SYNUCLEINOPATHY UNIV TOHOKU (JP) 2021-11-24 EP disclosed
CN-111440046-A Synthesis method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest peach leaf miner 塔里木大学 2020-07-24 CN disclosed
US-10709688-B2 Agent for treating synucleinopathy TOHOKU UNIVERSITY (JP) 2020-07-14 US disclosed
US-10709688-B2 Agent for treating synucleinopathy TOHOKU UNIVERSITY (JP) 2020-07-14 US disclosed
US-20190125726-A1 AGENT FOR TREATING SYNUCLEINOPATHY TOHOKU UNIVERSITY (JP) 2019-05-02 US disclosed
US-20190125726-A1 AGENT FOR TREATING SYNUCLEINOPATHY TOHOKU UNIVERSITY (JP) 2019-05-02 US disclosed
EP-3437640-A1 SYNUCLEINOPATHY THERAPEUTIC MEDICATION Tohoku University (JP) 2019-02-06 EP disclosed
EP-3437640-A1 SYNUCLEINOPATHY THERAPEUTIC MEDICATION Tohoku University (JP) 2019-02-06 EP disclosed
WO-2017171053-A1 SYNUCLEINOPATHY THERAPEUTIC MEDICATION 国立大学法人東北大学 2017-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10709688-B2 Agent for treating synucleinopathy SNCA, PARK7, SYNJ1 PPARA 2175/4885IL6ST 4310/4885FAAH 1647/4885
US-20190125726-A1 AGENT FOR TREATING SYNUCLEINOPATHY SNCA, PARK7, SYNJ1 PPARA 2175/4885IL6ST 4310/4885FAAH 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.