Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | PTPRF | P10586 | 5/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598485 | 0.88 | ALDH1A1 (0.39) | CREBBPALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL6600889 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2APTPRFPTPN2 | |
| SCHEMBL6598555 | 0.80 | PLK1 (0.42) | ALDH1A1MAPTKMT2APTPRFPTPN2 | |
| SCHEMBL6598772 | 0.80 | TP53 (0.45) | ALDH1A1MAPTKMT2APTPRFPTPN2 | |
| SCHEMBL6598766 | 0.77 | AKR1C3 (0.34) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL6599969 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6598130 | 0.76 | NPC1 (0.37) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6602677 | 0.75 | ELANE (0.33) | ALDH1A1MAPTKMT2APTPRFPTPN2 | |
| SCHEMBL6599202 | 0.74 | STAT3 (0.42) | ALDH1A1MAPTKMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL6598785 | 0.74 | NPC1 (0.37) | ALDH1A1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |