Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599836 | 0.90 | ALDH1A1 (0.34) | PLK1ALDH1A1POLBHSD17B10MEN1 | |
| SCHEMBL6599459 | 0.85 | NR3C1 (0.36) | ALDH1A1POLBHSD17B10MEN1KMT2A | |
| SCHEMBL6600889 | 0.85 | ALDH1A1 (0.38) | PLK1ALDH1A1POLBHSD17B10MEN1 | |
| SCHEMBL6601108 | 0.82 | ALDH1A1 (0.30) | ALDH1A1POLBHSD17B10 | |
| SCHEMBL6597688 | 0.80 | CREBBP (0.40) | ALDH1A1POLBHSD17B10MEN1KMT2A | |
| SCHEMBL7473185 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1POLBHSD17B10KMT2AMAPT | |
| SCHEMBL6598958 | 0.75 | ALDH1A1 (0.37) | ALDH1A1POLBHSD17B10MEN1KMT2A | |
| SCHEMBL6599969 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1POLBHSD17B10MEN1KMT2A | |
| SCHEMBL6598493 | 0.75 | ALDH1A1 (0.46) | PLK1ALDH1A1POLBHSD17B10 | |
| SCHEMBL6598720 | 0.73 | UGT2B7 (0.34) | POLBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |