Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23970158 | 0.96 | TBXAS1 (0.56) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL9910965 | 0.85 | TBXAS1 (0.61) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL16919628 | 0.84 | CFTR (0.48) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL14288463 | 0.84 | TBXAS1 (0.64) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL658876 | 0.83 | CFTR (0.57) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL21770565 | 0.82 | CFTR (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL11337414 | 0.82 | CFTR (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL23689571 | 0.82 | CFTR (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL24919838 | 0.82 | CFTR (0.47) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL7108264 | 0.81 | CFTR (0.44) | CFTRSLC6A2SLC6A4SLC6A3GOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | NDSU RESEARCH FOUNDATION | 2009-08-27 | — | — | US | claimed |
| US-8283432-B2 | Siloxane polymer containing tethered fluoroquinolone | NDSU RESEARCH FOUNDATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-8278400-B2 | Antifouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120046313-A1 | SILOXANE POLYMER CONTAINING TETHERED FLUOROQUINOLONE | NDSU RESEARCH FOUNDATION | 2012-02-23 | — | — | US | disclosed |
| US-20100204399-A1 | ANTIFOULING MATERIALS CONTAINING CATIONIC POLYSILOXANES | NDSU RESEARCH FOUNDATION | 2010-08-12 | — | — | US | disclosed |
| US-7771833-B2 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | NDSU RESEARCH FOUNDATION | 2009-08-27 | — | — | US | disclosed |
| EP-1879972-A4 | ANTI-FOULING MATERIALS CONTAINING POLYAMINE CROSS-LINKED POLYSILOXANES | NDSU RES FOUNDATION (US) | 2008-10-15 | — | — | EP | disclosed |
| EP-1879972-A1 | ANTI-FOULING MATERIALS CONTAINING POLYAMINE CROSS-LINKED POLYSILOXANES | NDSU Research Foundation (US) | 2008-01-23 | — | — | EP | disclosed |
| US-20070042199-A1 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION | 2007-02-22 | — | — | US | disclosed |
| WO-2006121937-A1 | ANTI-FOULING MATERIALS CONTAINING POLYAMINE CROSS-LINKED POLYSILOXANES | NDSU RESEARCH FOUNDATION (US) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046313-A1 | SILOXANE POLYMER CONTAINING TETHERED FLUOROQUINOLONE | QARS1, SEPTIN7, SMCHD1 | CFTR 47/4885SLC6A2 1270/4885SLC6A4 503/4885 |
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | PUF60, QARS1, SEPTIN7 | CFTR 220/4885SLC6A2 802/4885SLC6A4 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.