Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953334 | 0.86 | CHRM2 (0.43) | SLC6A2SLC6A4F2RL1FPR2 | |
| SCHEMBL7762331 | 0.83 | HRH1 (0.42) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6953526 | 0.82 | CFTR (0.46) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL6954460 | 0.82 | CFTR (0.46) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL659775 | 0.81 | CFTR (0.53) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL8088802 | 0.79 | FPR2 (0.43) | SMN1; SMN2F2RL1FPR2CYP19A1 | |
| SCHEMBL23970158 | 0.78 | TBXAS1 (0.56) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL1381367 | 0.76 | CFTR (0.53) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL4642031 | 0.74 | FPR2 (0.39) | F2RL1FPR2CYP19A1 | |
| SCHEMBL954734 | 0.73 | CHRM2 (0.45) | SLC6A2SLC6A4LMNAF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345953-A2 | KETOLIDE ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002032918-A2 | KETOLIDE ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-04-25 | — | — | WO | disclosed |