Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595796 | 0.87 | ALDH1A1 (0.67) | SIGMAR1ALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL2376923 | 0.79 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL28092846 | 0.79 | MEN1 (0.58) | SIGMAR1ALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL8595603 | 0.75 | SIGMAR1 (0.82) | SIGMAR1ALDH1A1MMP3HRH3 | |
| SCHEMBL19563417 | 0.74 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6107281 | 0.74 | KMT2A (0.76) | SIGMAR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL4763901 | 0.74 | SIGMAR1 (0.64) | SIGMAR1MEN1KMT2ACA12CA9 | |
| SCHEMBL8592975 | 0.73 | NPSR1 (0.56) | ALDH1A1GAAHTR2AHTR2C | |
| SCHEMBL14045852 | 0.73 | GAA (0.46) | SIGMAR1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL14045823 | 0.72 | GAA (0.43) | ALDH1A1MEN1KMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351958-B1 | IMIDAZOLO-5-YL-2-ANILINO-PYRIMIDINES AS AGENTS FOR THE INHIBITION OF THE CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2004-06-16 | — | — | EP | disclosed |