Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749735 | 0.80 | CYP2C19 (0.41) | — | |
| SCHEMBL13003189 | 0.78 | ELANE (0.37) | ELANECYP19A1ALDH1A1CYP1A2MEN1 | |
| SCHEMBL5690985 | 0.76 | CYP19A1 (0.50) | ELANECYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL18906449 | 0.74 | CYP1A2 (0.39) | CYP19A1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL1758179 | 0.73 | CYP1A2 (0.38) | CYP19A1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL18499747 | 0.71 | CYP19A1 (0.40) | GRM2CYP19A1ALDH1A1CYP1A2MEN1 | |
| SCHEMBL9181452 | 0.71 | CYP1A2 (0.40) | CYP19A1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL22963926 | 0.71 | ALDH1A1 (0.37) | CYP19A1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL18499720 | 0.71 | CYP19A1 (0.40) | GRM2CYP19A1ALDH1A1CYP1A2MEN1 | |
| SCHEMBL27576345 | 0.71 | CYP1A2 (0.40) | CYP19A1ALDH1A1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201664-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-6593323-B1 | Benzimidazole compound inhibitory action of forming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): | FUJI PHOTO FILM CO., LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1201664-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |