SCHEMBL659817

SCHEMBL659817

CC(C)C(C(=O)O)C(C(=O)O)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
SLC7A5 Q01650 2/20 0.47
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
FPR1 P21462 1/20 0.35
FPR2 P25090 1/20 0.35
TSHR P16473 1/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
GABRR1 P24046 2/20 0.35
RNPEP Q9H4A4 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16438180 1.00 TP53 (0.50) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL66413 0.92 TP53 (0.50) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL15113031 0.90 TP53 (0.42) TP53SLC7A5SLC1A3SLC1A2SLC1A1
Water SCHEMBL8870694 0.89 TP53 (0.47) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL18624675 0.87 TP53 (0.40) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL18624676 0.85 SLC7A5 (0.43) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL14790269 0.85 TP53 (0.38) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL17049853 0.83 TP53 (0.42) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL2297452 0.83 TP53 (0.50) TP53SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL15592505 0.83 TP53 (0.50) TP53SLC7A5SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081966-A Application method of composite external electron donor for controlling ethylene polymerization hydrogen regulation and comonomer distribution 中化泉州石化有限公司 2025-06-03 CN claimed
CN-120004935-A External electron donor, olefin polymerization catalyst system and application 中国石油天然气股份有限公司 2025-05-16 CN claimed
CN-118480148-A Ultra-high molecular weight PAO and preparation method thereof 中国科学院化学研究所 2024-08-13 CN claimed
EP-3397657-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2024-06-12 EP claimed
CN-117801141-A Catalyst system for olefin polymerization reaction, prepolymerized catalyst composition and application 中国石油化工股份有限公司 2024-04-02 CN claimed
CN-116410357-A Multi-element external electron donor composition and application thereof 中国石油天然气股份有限公司 2023-07-11 CN claimed
CN-116003656-A External electron donor composition, ziegler-Natta catalyst composition and propylene polymerization process 湖北华邦化学有限公司 2023-04-25 CN claimed
EP-3059263-B1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
CN-109096421-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096419-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-104513330-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
EP-2399902-B1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANO SUCCINIC ACID DIESTERS CHINA PETROLEUM & CHEMICAL (CN) 2014-11-26 EP claimed
US-8669392-B2 Process for preparing 2,3-di-non-straight-alkyl-2-cyanosuccinic acid diesters CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-03-11 US claimed
CN-101811982-B 2,3-diisopropyl-2.3-dicyano-diethyl succinate compound, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2013-02-06 CN claimed
US-20120046490-A1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANOSUCCINIC ACID DIESTERS CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-02-23 US claimed
EP-2399902-A1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANO SUCCINIC ACID DIESTERS China Petroleum & Chemical Corporation (CN) 2011-12-28 EP claimed
EP-1525231-B1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2007-12-05 EP claimed
EP-1088009-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-08-02 EP claimed
EP-1525231-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-04-27 EP claimed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046490-A1 PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANOSUCCINIC ACID DIESTERS ACMSD, ADSL, CNDP2 TP53 4544/4885SLC7A5 594/4885SLC1A3 904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.