Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | LMNA | P02545 | 10/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031351 | 0.80 | CYP1A2 (0.61) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL2998447 | 0.79 | EGFR (0.68) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL4357581 | 0.79 | ALDH1A1 (0.69) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL25844376 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL31031354 | 0.75 | CYP1A2 (0.55) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL2880252 | 0.75 | CYP1A2 (0.55) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL4359084 | 0.73 | CYP1A2 (0.75) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL4353312 | 0.73 | CYP1A2 (0.75) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL2184445 | 0.73 | EGFR (0.68) | CYP1A2CYP3A4CLK4ALDH1A1LMNA | |
| SCHEMBL2993744 | 0.72 | IRAK4 (0.53) | CYP1A2CYP3A4CLK4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |