Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 12/20 | 0.59 |
| ▸ | LMNA | P02545 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031351 | 0.80 | CYP1A2 (0.61) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL2998447 | 0.79 | EGFR (0.68) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL6598291 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL4357581 | 0.79 | ALDH1A1 (0.69) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL13599958 | 0.76 | PARP1 (0.44) | CYP1A2CLK4LMNAALDH1A1HSD17B10 | |
| SCHEMBL30317618 | 0.75 | PARP1 (0.47) | LMNAALDH1A1GLAHPGDEGFR | |
| SCHEMBL1192531 | 0.75 | PARP1 (0.47) | LMNAALDH1A1GLAHPGDEGFR | |
| SCHEMBL31031354 | 0.75 | CYP1A2 (0.55) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL2880252 | 0.75 | CYP1A2 (0.55) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL4741965 | 0.75 | EGFR (0.63) | LMNAALDH1A1TP53HIF1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701371-B2 | ENPP1 inhibitors and their use for the treatment of cancer | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701371-B2 | ENPP1 inhibitors and their use for the treatment of cancer | ENPP1, ENPP3, ENTPD1 | CYP1A2 4507/4885CYP3A4 4454/4885CLK4 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.