Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | SI | P14410 | 1/20 | 0.64 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydantoin SCHEMBL5185641 | 0.87 | GSK3A (0.48) | GSK3AGSK3BMGAMGAASI | |
| Thiazolidinedione SCHEMBL8759425 | 0.81 | GSK3A (0.59) | GSK3AGSK3BMGAMGAASI | |
| Thiazolidinedione SCHEMBL4828229 | 0.80 | GSK3A (1.00) | GSK3AGSK3BMGAMGAASI | |
| SCHEMBL962066 | 0.80 | — | — | |
| Thiazolidinedione SCHEMBL135101 | 0.80 | — | — | |
| SCHEMBL123971 | 0.80 | — | — | |
| Thiazolidinedione SCHEMBL4895522 | 0.80 | — | — | |
| Thiazolidinedione SCHEMBL5043 | 0.80 | — | — | |
| SCHEMBL4119295 | 0.80 | — | — | |
| Thiazolidinedione SCHEMBL5795315 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201664-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-09-08 | — | — | EP | claimed |
| CN-101683528-A | Novel ppar ligands that do not cause fluid retention, edema or congestive heart failure | BETHESDA PHARMACEUTICALS INC | 2010-03-31 | — | — | CN | disclosed |