Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19111825 | 0.78 | TSHR (0.49) | ALDH1A1KMT2ATDP1GAAMEN1 | |
| SCHEMBL7288149 | 0.76 | EPHX1 (0.39) | ALDH1A1ELANEKMT2ASMN1; SMN2CTSC | |
| SCHEMBL23356900 | 0.76 | DPP4 (0.49) | ALDH1A1ELANERAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL4447785 | 0.76 | DPP4 (0.49) | ALDH1A1ELANERAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2016284 | 0.76 | DPP4 (0.49) | ALDH1A1ELANERAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6597169 | 0.75 | ALDH1A1 (0.41) | ALDH1A1ELANERAB9AKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10521985 | 0.75 | DPP4 (0.50) | ALDH1A1ELANERAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9432280 | 0.74 | MEN1 (0.48) | ALDH1A1RAB9AKMT2ASMN1; SMN2POLB | |
| SCHEMBL27839066 | 0.74 | SMN1; SMN2 (0.35) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6593799 | 0.74 | ALDH1A1 (0.40) | ALDH1A1ELANERAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228061-A4 | DIPEPTIDYL PEPTIDASE IV INHIBITORS AND METHODS OF MAKING AND USING DIPEPTIDYL PEPTIDASE IV INHIBITORS | GUILFORD PHARM INC (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1228061-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS AND METHODS OF MAKING AND USING DIPEPTIDYL PEPTIDASE IV INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001034594-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS AND METHODS OF MAKING AND USING DIPEPTIDYL PEPTIDASE IV INHIBITORS | GUILFORD PHARMACEUTICALS, INC. (US) | 2001-05-17 | — | — | WO | disclosed |