Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163828 | 0.81 | KMT2A (0.59) | KMT2AOPRK1MEN1ELANEABCG2 | |
| SCHEMBL2256399 | 0.81 | KMT2A (0.56) | KMT2AOPRK1MEN1ELANEABCG2 | |
| SCHEMBL29532414 | 0.81 | KMT2A (0.67) | KMT2AOPRK1MEN1ELANEABCG2 | |
| SCHEMBL10815968 | 0.81 | ACHE (0.49) | KMT2AOPRK1S100A4ACHESMN1; SMN2 | |
| SCHEMBL2263219 | 0.81 | KMT2A (0.67) | KMT2AOPRK1MEN1ELANEABCG2 | |
| SCHEMBL31399874 | 0.78 | EIF4A1 (0.51) | KMT2AOPRK1MEN1ELANEABCG2 | |
| SCHEMBL4966085 | 0.78 | KMT2A (0.52) | KMT2AOPRK1MEN1ABCG2ACHE | |
| SCHEMBL6593674 | 0.78 | KMT2A (0.52) | KMT2AOPRK1MEN1ELANEABCG2 | |
| SCHEMBL16415885 | 0.78 | KMT2A (0.49) | KMT2AOPRK1MEN1ELANEACHE | |
| SCHEMBL7821797 | 0.76 | KMT2A (0.51) | KMT2AOPRK1MEN1ELANEABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |