Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599023 | 0.81 | HTR1A (1.00) | HTR1ADRD2HTR1D | |
| Hydrochloric Acid SCHEMBL6597603 | 0.80 | HTR1A (0.98) | HTR1ADRD2HTR1D | |
| SCHEMBL6597937 | 0.73 | HTR1A (1.00) | HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6598673 | 0.73 | HTR1A (0.98) | HTR1AHTR1D | |
| SCHEMBL6598607 | 0.73 | HTR1A (0.58) | HTR1ADRD2 | |
| SCHEMBL8129914 | 0.70 | HTR1A (0.62) | HTR1ADRD2 | |
| SCHEMBL7458206 | 0.69 | HTR1A (0.78) | HTR1ADRD2HTR1DHTR2BLMNA | |
| SCHEMBL6598764 | 0.69 | HTR1A (1.00) | HTR1ADRD2HTR1D | |
| SCHEMBL6486972 | 0.68 | HTR1A (0.79) | HTR1ADRD2HTR1DHTR2B | |
| Benzene SCHEMBL10433203 | 0.68 | HTR1A (0.79) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |