Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129914 | 0.89 | HTR1A (0.62) | HTR1ADRD2DRD3ADRA1AHTR2A | |
| SCHEMBL27454683 | 0.74 | KDM4E (0.65) | HTR1ADRD2DRD3DRD4ADRA1A | |
| SCHEMBL6597937 | 0.74 | HTR1A (1.00) | HTR1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27508537 | 0.74 | KDM4E (0.64) | HTR1ADRD2DRD3DRD4HTR2A | |
| Hydrochloric Acid SCHEMBL6598673 | 0.73 | HTR1A (0.98) | HTR1AALDH1A1 | |
| SCHEMBL3162960 | 0.73 | DRD2 (0.76) | DRD2DRD3DRD4 | |
| SCHEMBL6598604 | 0.73 | HTR1A (0.68) | HTR1ADRD2 | |
| SCHEMBL19580052 | 0.72 | DRD2 (0.81) | HTR1ADRD2DRD3DRD4ADRA1A | |
| SCHEMBL6599023 | 0.72 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL28972777 | 0.72 | HTR1A (0.67) | HTR1ADRD2DRD3DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |