Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CCNC | P24863 | 6/20 | 0.53 |
| ▸ | CDK8 | P49336 | 6/20 | 0.53 |
| ▸ | IGF1R | P08069 | 4/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750424 | 0.86 | CCNC (0.72) | EGFRCCNCCDK8IGF1RKDM4E | |
| SCHEMBL13496026 | 0.84 | PKM (0.64) | EGFRPKMIGF1RBACE1KDM4E | |
| SCHEMBL29337531 | 0.83 | HTR1A (0.68) | PKMCCNCCDK8KDM4EMEN1 | |
| SCHEMBL27174112 | 0.83 | PKM (0.59) | PKMCCNCCDK8KDM4EMEN1 | |
| SCHEMBL4823156 | 0.82 | EGFR (0.43) | EGFRPKMCCNCCDK8KDM4E | |
| SCHEMBL13496036 | 0.82 | PKM (0.62) | EGFRPKMIGF1RBACE1KDM4E | |
| SCHEMBL31197362 | 0.82 | HTR1A (0.69) | EGFRPKMCCNCCDK8IGF1R | |
| SCHEMBL3051350 | 0.82 | HTR1A (0.69) | EGFRPKMCCNCCDK8IGF1R | |
| SCHEMBL21750414 | 0.80 | CCNC (0.77) | PKMCCNCCDK8ALDH1A1LMNA | |
| SCHEMBL6617291 | 0.79 | NQO2 (0.67) | EGFRKDM4EMEN1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |