Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ATF4 | P18848 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5358894 | 0.99 | MEN1 (0.38) | MEN1KMT2AMAPK8HPGDHTT | |
| Pyrazole SCHEMBL1193843 | 0.93 | MEN1 (0.34) | MEN1KMT2AMAPK8HPGDHTT | |
| SCHEMBL6597984 | 0.86 | MAPK8 (0.39) | MEN1KMT2AMAPK8ALDH1A1KDM5A | |
| Hydrochloric Acid SCHEMBL1194003 | 0.85 | MAPK8 (0.39) | MEN1KMT2AMAPK8LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6621921 | 0.83 | CPT2 (0.33) | MEN1KMT2AHTTRAB9ALMNA | |
| Hydrochloric Acid SCHEMBL6597610 | 0.82 | MAPK8 (0.36) | MEN1KMT2AMAPK8ALDH1A1 | |
| SCHEMBL6598418 | 0.80 | KMT2A (0.36) | MEN1KMT2AMAPK8HPGDHTT | |
| SCHEMBL6596042 | 0.80 | KMT2A (0.48) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27534077 | 0.80 | MLLT1 (0.37) | KMT2AMAPK8ALDH1A1CNR2POLB | |
| Bromide SCHEMBL1194131 | 0.80 | KMT2A (0.35) | MEN1KMT2AMAPK8HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |