Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5364641 | 0.99 | KMT2A (0.35) | KMT2AMAPK8CYP3A4CYP2D6SLC6A2 | |
| Bromide SCHEMBL1194131 | 0.99 | KMT2A (0.35) | KMT2AMAPK8CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6597480 | 0.87 | MAPK8 (0.39) | KMT2AMAPK8CYP3A4CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL1194126 | 0.87 | MAPK8 (0.38) | KMT2AMAPK8CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6599056 | 0.84 | CYP3A4 (0.39) | KMT2AMAPK8CYP3A4HPGDRAB9A | |
| SCHEMBL6597741 | 0.84 | LMNA (0.41) | KMT2ACYP2D6RAB9AHTTKDM4E | |
| Hydrochloric Acid SCHEMBL1195003 | 0.83 | CYP3A4 (0.39) | KMT2AMAPK8CYP3A4HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL1194038 | 0.83 | LMNA (0.42) | KMT2ACYP2D6HTTKDM4EAPOBEC3A | |
| SCHEMBL6598655 | 0.80 | MEN1 (0.38) | KMT2AMAPK8HPGDRAB9AHTT | |
| Hydrochloric Acid SCHEMBL5358894 | 0.80 | MEN1 (0.38) | KMT2AMAPK8HPGDRAB9AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |