Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1194003 | 0.99 | MAPK8 (0.39) | MAPK8BRD4MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6597610 | 0.94 | MAPK8 (0.36) | MAPK8BRD4MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL27534077 | 0.90 | MLLT1 (0.37) | MAPK8ALDH1A1KMT2AROCK2ROCK1 | |
| SCHEMBL6598655 | 0.86 | MEN1 (0.38) | MAPK8MEN1ALDH1A1KMT2AKDM5A | |
| Hydrochloric Acid SCHEMBL5358894 | 0.85 | MEN1 (0.38) | MAPK8MEN1ALDH1A1KMT2AROCK2 | |
| SCHEMBL6598432 | 0.83 | KMT2A (0.43) | MEN1ALDH1A1KMT2AEPHX2GAA | |
| SCHEMBL14313591 | 0.82 | MAPK8 (0.47) | MAPK8MEN1ALDH1A1KMT2AKDM5B | |
| Hydrochloric Acid SCHEMBL1194824 | 0.82 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2AEPHX2GAA | |
| SCHEMBL6596014 | 0.82 | KMT2A (0.47) | MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7070348 | 0.82 | HSP90AA1 (0.44) | ALDH1A1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |