Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.75 |
| ▸ | HTR1D | P28221 | 2/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598700 | 1.00 | HTR1A (0.75) | HTR1AHTR1DTP53MAPTDRD4 | |
| SCHEMBL6597325 | 0.86 | HTR1A (1.00) | HTR1AHTR1DTP53MAPT | |
| Hydrochloric Acid SCHEMBL6598512 | 0.85 | HTR1A (0.98) | HTR1AHTR1DTP53MAPT | |
| SCHEMBL6600129 | 0.81 | HTR1A (0.55) | HTR1AHTR1DMAPTDRD4DRD2 | |
| SCHEMBL6600132 | 0.81 | HTR1A (0.55) | HTR1AHTR1DMAPTDRD4DRD2 | |
| SCHEMBL6351477 | 0.80 | DRD4 (0.76) | HTR1AMAPTDRD4DRD2DRD3 | |
| SCHEMBL6351475 | 0.80 | DRD4 (0.76) | HTR1AMAPTDRD4DRD2DRD3 | |
| SCHEMBL8120660 | 0.78 | DRD4 (0.58) | HTR1AHTR1DMAPTDRD4DRD2 | |
| Hydrochloric Acid SCHEMBL6600035 | 0.76 | HTR1A (0.98) | HTR1AHTR1DMAPT | |
| SCHEMBL7988547 | 0.76 | HTR1A (0.81) | HTR1AHTR1DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | claimed |
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | claimed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | claimed |
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |