Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598743 | 1.00 | TYR (0.40) | TYRPTGS2EPHX2CA2CA1 | |
| SCHEMBL20478181 | 0.87 | KDM4E (0.41) | PTGS2CA2CA1CA9CA12 | |
| SCHEMBL6597960 | 0.82 | TYR (0.43) | TYRCA2CA1CA9CA12 | |
| SCHEMBL20478167 | 0.81 | PTGDR2 (0.43) | PTGS2CA2CA1CA9CA12 | |
| SCHEMBL20478180 | 0.81 | CA12 (0.41) | PTGS2CA2CA1CA9CA12 | |
| SCHEMBL5598080 | 0.80 | PTGDR2 (0.46) | PTGS2CA2CA1CA9CA12 | |
| SCHEMBL7027323 | 0.77 | ALDH1A1 (0.47) | TYRPTGS2CA2CA1CA9 | |
| SCHEMBL2047774 | 0.75 | TRPA1 (0.50) | ALDH1A1GAAKDM4ELMNATP53 | |
| SCHEMBL6987737 | 0.75 | TYR (0.38) | TYRPTGS2CA2CA1CA9 | |
| SCHEMBL19249421 | 0.75 | TYR (0.48) | TYRPTGS2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317425-B1 | RESORCINOL DERIVATIVES | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1317425-A2 | RESORCINOL DERIVATIVES | Pfizer Products Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020474-A2 | RESORCINOL DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2002-03-14 | — | — | WO | disclosed |