Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366940 | 0.91 | DPP4 (0.49) | KMT2ATDP1DPP4KCNH2DPP7 | |
| SCHEMBL5366944 | 0.91 | DPP4 (0.49) | KMT2ATDP1DPP4KCNH2DPP7 | |
| SCHEMBL5356347 | 0.84 | KMT2A (0.48) | HTR1AHTR7DRD2KMT2ATDP1 | |
| SCHEMBL6599031 | 0.84 | KMT2A (0.48) | HTR1AHTR7DRD2KMT2ATDP1 | |
| SCHEMBL5356341 | 0.84 | KMT2A (0.48) | HTR1AHTR7DRD2KMT2ATDP1 | |
| SCHEMBL5355689 | 0.84 | HSD17B1 (0.41) | DRD2ADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL5355687 | 0.84 | HSD17B1 (0.41) | DRD2ADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL5359472 | 0.81 | KMT2A (0.40) | HTR1AHTR7DRD2HTR6ADRA1D | |
| SCHEMBL5359477 | 0.81 | KMT2A (0.40) | HTR1AHTR7DRD2HTR6ADRA1D | |
| SCHEMBL5363005 | 0.80 | KMT2A (0.52) | HTR7DRD2HTR6KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317425-B1 | RESORCINOL DERIVATIVES | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |