Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.48 |
| ▸ | CTSS | P25774 | 13/20 | 0.48 |
| ▸ | CTSL | P07711 | 11/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 3/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590008 | 0.93 | CTSK (0.46) | CTSKCTSSCTSLUTS2RKLK5 | |
| SCHEMBL6594823 | 0.91 | CTSL (0.57) | CTSKCTSSCTSL | |
| SCHEMBL6588976 | 0.90 | CTSL (0.53) | CTSKCTSSCTSL | |
| SCHEMBL6592443 | 0.90 | CTSL (0.49) | CTSKCTSSCTSLUTS2R | |
| SCHEMBL6592614 | 0.88 | CTSK (0.38) | CTSKCTSSCTSLUTS2RKLK5 | |
| SCHEMBL6483862 | 0.87 | CTSL (0.64) | CTSKCTSSCTSL | |
| SCHEMBL6590299 | 0.87 | CTSL (0.51) | CTSKCTSSCTSLUTS2R | |
| SCHEMBL6594147 | 0.87 | CTSK (0.46) | CTSKCTSSCTSLKLK5SCN9A | |
| SCHEMBL6591317 | 0.87 | CTSK (0.38) | CTSKCTSSCTSLUTS2RKLK5 | |
| SCHEMBL6593114 | 0.86 | CTSK (0.47) | CTSKCTSSCTSLSCN9ACTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178986-B1 | FURANONE DERIVATIVES AS INHIBITORS OF CATHEPSIN S | MEDIVIR UK LTD (GB) | 2004-02-25 | — | — | EP | claimed |